Profiles of BBDC Members Primarily Involved In Diabetes Research

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Nunes Vasconcelos, Sara - PhD

University of Toronto Appointment(s): Assistant Professor, Institute of Biomaterials and Biomedical Engineering
Laboratory of Medicine and Pathobiology

Other Appointment(s): Assistant Scientist, Division of Experimental Therapeutics, Toronto General Research Institute, University Health Network
Member of the Heart & Stroke/Richard Lewar Centre of Excellence (HSRLCE), University of Toronto
Member of Ontario Institute for Regenerative Medicine (OIRM)

Contact Information:
101 College St.
Toronto, ON   M5G 1L7

Phone: (416) 581-7527

Diabetes Related Research Activities:

We are investigating how diabetes affects vessel formation (angiogenesis and arterio-venous specification) and its implications in tissue engineering for regenerative medicine. Moreover, we are investigating the direct effects of diabetes and diabetes-related drugs on crdiovascular health including human stem cell-derived cardiomyocyte organoid models.

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Oh, Paul - MD, MSc

University of Toronto Appointment(s): Associate Professor, Department of Medicine

Other Appointment(s): Medical Director and GoodLife Fitness Chair
Peter Munk Cardiac Centre and Toronto Rehabilitation Institute
University Health Network

Contact Information:
Toronto Rehab - Rumsey Centre
347 Rumsey Rd.
Toronto, ON   M4G 1R7

Phone: 416-597-3422

Diabetes Related Research Activities:

  • Exercise and lifestyle interventions for the prevention and management of diabetes
  • Patient education to enhance self management and health beahviours

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Ohashi, Pamela S. - PhD, FRSC

University of Toronto Appointment(s): Professor, Departments of Medical Biophysics and Immunology

Other Appointment(s): Director, Immune Therapy Program; Co-Director, Campbell Family Institute for Breast Cancer Research; Senior Scientist, Ontario Cancer Institute/Princess Margaret Hospital, University Health Network

Contact Information:
Princess Margaret Hospital
620 University Ave., 10th Floor, Room 1030
Toronto, ON   M5G 2C1

Phone: (416) 946-2357
Fax: (416) 204-2276

Diabetes Related Research Activities:

The major focus of my lab is to understand the mechanisms of death and differentiation in immature and mature T cells. In particular, an emphasis is placed on understanding the molecular events that direct T cell fate towards either tolerance or activation. These questions are investigated in the context of understanding autoimmunity (diabetes) and tumor immune surveillance in vivo.

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Ostrow, Brian - MD, FRCSC

University of Toronto Appointment(s): Adjunct Assistant Professor, Department of Surgery

Other Appointment(s): Project Coordinator, Guyana Diabetes Care Project

Contact Information:
44 Suffolk St. W.
Guelph, ON   N1H 2H8

Phone: (519) 821-4625
Fax: (519) 824-3852

Diabetes Related Research Activities:

Member of the Banting & Best Diabetes Centre International Diabetes Collaboration research program.

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Palmert, Mark R. - MD, PhD

University of Toronto Appointment(s): Associate Professor, Department of Pediatrics and Physiology

Other Appointment(s): Senior Associate Scientist, Genetics & Genome Biology Program, Hospital For Sick Children

Contact Information:
The Hospital for Sick Children
555 University Avenue
Toronto, ON   M5G 1X8

Phone: (416) 813-6217
Fax: (416) 813-6304

Diabetes Related Research Activities:

I care for children and adolescents with type 1 and type 2 diabetes mellitus. I have been involved in diabetes related clinical research as a Principal Investigator in the NIH multicentered trial entitled Treatment Options for Type 2 Diabetes in adolescents and Youth (TODAY), which was designed to identify best ways to treat type 2 diabetes in youth. I have also been Principal Investigator the Clinical Coordinating Center for the NIH/NIDDK funded Epidemiology of Diabetes Intervention and Complications (DCCT/EDIC).
Currently, my diabetes related research includes membership in the Hvidoere Study Group of Childhood Diabetes and using technology to enhance diabetes self-management.  We and collaborators are performing a randomized clinical trial designed to test an iPhone based system to help adolescents manage their diabetes more effectively.
I addition to these clinical research activities, I also direct lab-based research investigating the effects that in utero exposures on adult outcomes, such as development of diabetes and abnormalities of bone and metabolism.

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