Profiles of BBDC Members Primarily Involved In Diabetes Research

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Ohashi, Pamela S. - PhD, FRSC

University of Toronto Appointment(s): Professor, Departments of Medical Biophysics and Immunology

Other Appointment(s): Director, Immune Therapy Program; Co-Director, Campbell Family Institute for Breast Cancer Research; Senior Scientist, Ontario Cancer Institute/Princess Margaret Hospital, University Health Network

Contact Information:
Princess Margaret Hospital
620 University Ave., 10th Floor, Room 1030
Toronto, ON   M5G 2C1

Phone: (416) 946-2357
Fax: (416) 204-2276

Diabetes Related Research Activities:

The major focus of my lab is to understand the mechanisms of death and differentiation in immature and mature T cells. In particular, an emphasis is placed on understanding the molecular events that direct T cell fate towards either tolerance or activation. These questions are investigated in the context of understanding autoimmunity (diabetes) and tumor immune surveillance in vivo.

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Ostrow, Brian - MD, FRCSC

University of Toronto Appointment(s): Adjunct Assistant Professor, Department of Surgery

Other Appointment(s): Project Coordinator, Guyana Diabetes Care Project

Contact Information:
44 Suffolk St. W.
Guelph, ON   N1H 2H8

Phone: (519) 821-4625
Fax: (519) 824-3852

Diabetes Related Research Activities:

Member of the Banting & Best Diabetes Centre International Diabetes Collaboration research program.

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Palmert, Mark R. - MD, PhD

University of Toronto Appointment(s): Associate Professor, Department of Pediatrics and Physiology

Other Appointment(s): Senior Associate Scientist, Genetics & Genome Biology Program, Hospital For Sick Children

Contact Information:
The Hospital for Sick Children
555 University Avenue
Toronto, ON   M5G 1X8

Phone: (416) 813-6217
Fax: (416) 813-6304

Diabetes Related Research Activities:

I care for children and adolescents with type 1 and type 2 diabetes mellitus. I have been involved in diabetes related clinical research as a Principal Investigator in the NIH multicentered trial entitled Treatment Options for Type 2 Diabetes in adolescents and Youth (TODAY), which was designed to identify best ways to treat type 2 diabetes in youth. I have also been Principal Investigator the Clinical Coordinating Center for the NIH/NIDDK funded Epidemiology of Diabetes Intervention and Complications (DCCT/EDIC).
Currently, my diabetes related research includes membership in the Hvidoere Study Group of Childhood Diabetes and using technology to enhance diabetes self-management.  We and collaborators are performing a randomized clinical trial designed to test an iPhone based system to help adolescents manage their diabetes more effectively.
I addition to these clinical research activities, I also direct lab-based research investigating the effects that in utero exposures on adult outcomes, such as development of diabetes and abnormalities of bone and metabolism.

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Parra, Esteban J. - PhD

University of Toronto Appointment(s): Associate Professor, Department of Anthropology

Contact Information:
University of Toronto at Mississauga, Room 352 Health Sciences Complex
3359 Mississauga Road North
Mississauga, ON   L5L 1C6

Phone: (905) 828-3889
Fax: (905) 828-3792

Diabetes Related Research Activities:

Type 2 diabetes is one of the most serious public health issues in Canada and on a global scale. There are striking differences in prevalence among ethnic groups. The prevalence of type 2 diabetes among Aboriginal people is higher than in the general population, and elevated risk has also been described for other groups, such as Hispanics. One of the major goals of Dr. Parra's research is to identify type 2 diabetes genetic risk factors in Hispanic populations, using different approaches, such as candidate gene studies, admixture mapping and genome-wide association.

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Parry, Monica - MEd MSc PhD

University of Toronto Appointment(s): Assistant Professor
Leadership Team
Director, Nurse Practitioner Programs
Lawrence S. Bloomberg Faculty of Nursing

Other Appointment(s): Nurse Practitioner - Adult, Cardiac Surgery, Kingston General Hospital

Contact Information:
Suite 130
155 College Street
Toronto, ON   M5T 1P8

Phone: (416) 946-3561
Fax: (416) 978-8222

Diabetes Related Research Activities:

I have worked as a Nurse Practitioner in Cardiac Surgery since 1998, and in my role have cared for many individuals with diabetes (T2DM). Many patients who have sternal wound infections have diabetes, and many individuals have poor blood sugar control following cardiac surgery. Collaborating with an Endocrinilogist I helped to develop standardized pre-printed orders to help manage blood sugars for our patient's who had T2DM. I am interested in the prevention of complications in individuals with diabetes, with a specific interest is in the prevention of cardiovascular disease. I am a co-investigator and member of the steering committee for a CIHR-funded team grant (PI Dr. Stewart Harris) investigating diabetes in several aboriginal communities in Canada. Current efforts are directed to the detection of autonomic neuropathies using impedance cardiography.

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