Profiles of BBDC Members Primarily Involved In Diabetes Research

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Palmert, Mark R. - MD, PhD

University of Toronto Appointment(s): Associate Professor, Department of Pediatrics and Physiology

Other Appointment(s): Senior Associate Scientist, Genetics & Genome Biology Program, Hospital For Sick Children

Contact Information:

Division of Endocrinology
The Hospital for Sick Children
555 University Avenue
Toronto, Ontario M5G 1X8

Phone: 416-813-6217
Fax: 416-813-6304

Diabetes Related Research Activities:

I care for children and adolescents with type 1 and type 2 diabetes mellitus. I have been involved in diabetes related clinical research as a Principal Investigator in the NIH multicentered trial entitled Treatment Options for Type 2 Diabetes in adolescents and Youth (TODAY), which was designed to identify best ways to treat type 2 diabetes in youth. I have also been Principal Investigator the Clinical Coordinating Center for the NIH/NIDDK funded Epidemiology of Diabetes Intervention and Complications (DCCT/EDIC).
Currently, my diabetes related research includes membership in the Hvidoere Study Group of Childhood Diabetes and using technology to enhance diabetes self-management.  We and collaborators are performing a randomized clinical trial designed to test an iPhone based system to help adolescents manage their diabetes more effectively.
I addition to these clinical research activities, I also direct lab-based research investigating the effects that in utero exposures on adult outcomes, such as development of diabetes and abnormalities of bone and metabolism.

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Parra, Esteban J. - PhD

University of Toronto Appointment(s): Associate Professor, Department of Anthropology

Contact Information:
University of Toronto at Mississauga, room 352 Health Sciences Complex
3359 Mississauga Road North
Mississauga, ON   L5L 1C6

Phone: 905-828-3889
Fax: 905-828-3792

Diabetes Related Research Activities:

Type 2 diabetes is one of the most serious public health issues in Canada and on a global scale. There are striking differences in prevalence among ethnic groups. The prevalence of type 2 diabetes among Aboriginal people is higher than in the general population, and elevated risk has also been described for other groups, such as Hispanics. One of the major goals of Dr. Parra's research is to identify type 2 diabetes genetic risk factors in Hispanic populations, using different approaches, such as candidate gene studies, admixture mapping and genome-wide association.

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Parry, Monica - MEd MSc PhD

University of Toronto Appointment(s): Assistant Professor
Leadership Team
Director, Nurse Practitioner Programs
Lawrence S. Bloomberg Faculty of Nursing

Other Appointment(s): Nurse Practitioner - Adult, Cardiac Surgery, Kingston General Hospital

Contact Information:
Suite 130
155 College Street
Toronto, ON   M5T 1P8

Phone: 416.946.3561
Fax: 416.978.8222

Diabetes Related Research Activities:

I have worked as a Nurse Practitioner in Cardiac Surgery since 1998, and in my role have cared for many individuals with diabetes (T2DM). Many patients who have sternal wound infections have diabetes, and many individuals have poor blood sugar control following cardiac surgery. Collaborating with an Endocrinilogist I helped to develop standardized pre-printed orders to help manage blood sugars for our patient's who had T2DM. I am interested in the prevention of complications in individuals with diabetes, with a specific interest is in the prevention of cardiovascular disease. I am a co-investigator and member of the steering committee for a CIHR-funded team grant (PI Dr. Stewart Harris) investigating diabetes in several aboriginal communities in Canada. Current efforts are directed to the detection of autonomic neuropathies using impedance cardiography.

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Paterson, Andrew D. - MB ChB, BSc(Hons)

University of Toronto Appointment(s): Associate Professor, Dalla Lana School of Public Health

Other Appointment(s): Senior Scientist, Program in Genetics and Genome Biology, Hospital for Sick Children

Contact Information:
686 Bay St
Toronto, ON   M5G oA4

Phone: 416-813-6994
Fax: 416-813-2150

Diabetes Related Research Activities:

Long-term complications of diabetes, including eye and kidney disease cluster in families suggesting that genetic factors may be involved. Using DNA from large numbers of people with diabetes who have their complications measured, we are using high throughput methods to measure all of the common genetic variation in the human genome to identify which ones are associated with specific complications. In addition, we are identifying genetic loci that are associated with the major risk factors for diabetes complications – glycemia, blood pressure, body composition and lipids.

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Perkins, Bruce - MD

University of Toronto Appointment(s): Assistant Professor, Department of Medicine, Division of Endocrinology and Metabolism

Other Appointment(s): Staff Physician, University Health Network

Contact Information:

Leadership Sinai Centre for Diabetes
Mount Sinai Hospital
Room L5-210
60 Murray Street
Toronto, ON  M5T 3L9

Phone: (416) 586-8763

Diabetes Related Research Activities:

My research initiatives focus on using epidemiological techniques to explore the natural history of diabetes complications and novel strategies for their prevention. My major clinical research areas include:
Characterizing the natural history of diabetic polyneuropathy and defining the best methods for clinical assessment.
Exploring the pattern of renal function decline and its determinants early in the course of nephropathy in type 1 diabetes.
Diabetes technologies, including the process of care for intensive insulin therapy.

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