Member Profile Page
Bolz, Steffen-Sebastian - MD, PhD
University of Toronto Appointment(s): Associate Professor and Associate Chair, Research, Department of Physiology
University of Toronto
Medical Sciences Building, Room 3326
1 King's College Circle
Toronto, ON M5S 1A8
Diabetes Related Research Activities:
My laboratory group recently started two projects that are related to diabetes:
1) The first project aims to understand the molecular signalling that underlies diabetes-associated microvascular structural and functional changes. Our special focus herein is on the role of microvascular sphingosine-1-phosphate signaling.
2) The second project aims to understand how heart failure affects the signalling network that ultimately controls blood glucose homeostasis. The special focus here is on the effects of TNFalpha on insulin and GLP-1 secretion.