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Bendeck, Michelle P. - PhD

University of Toronto Appointment(s): Professor and Research Director, Department of Laboratory Medicine and Pathobiology

Other Appointment(s): Career Investigator, Heart and Stroke Foundation of Ontario

Contact Information:
Medical Sciences Building, Room 6217
1 KIng's College Circle
Toronto, ON   M5S 1A8
Phone: 416-946-7133
Fax: 416-978-5959

Diabetes Related Research Activities:

The main focus of research in my lab is on atherosclerosis and specifically on interactions between cells and extracellular matrix during vascular remodeling. We are investigating mechanisms of vessel wall thickening and remodeling using experimental models of arterial injury in mouse, rat and rabbit, studying the role of extracellular matrix, cell-surface integrin receptors, the novel discoidin-domain receptors and MMPs in mediating SMC responses.  In collaboration with Dr. Adria Giacca, we are studying the effect of high glucose and insulin on SMC growth and matrix remodeling in atherosclerosis.

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