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Woo, Minna - MD, FRCPC, PhD

University of Toronto Appointment(s): Professor, Department of Medicine, Division of Endocrinology & Metabolism; and Departments of IMS, Medical Biophysics and Immunology

Other Appointment(s): Head, Division of Endocrinology and Metabolism, University Health Network/Mount Sinai Hospital
Scientist, Toronto General Research Institute, University Health Network

Contact Information:
Toronto Medical Discovery Tower, Room 10-353
101 College Street
Toronto, ON   M5G 1L7
Phone: (416) 340-4125

Diabetes Related Research Activities:

The major research focus in the Woo laboratory is to elucidate molecular mechanisms that determine pathogenesis of insulin resistance and type 2 diabetes. Our research interests include elucidating mechanisms of islet apoptosis and survival in physiological and diabetic states. We are interested in many of the fundamental genes involved in cell survival and apoptosis such as caspases, tumour suppressors and oncogenes. Many of these fundamental genes have essential physiological roles in metabolic tissues such as liver, muscle, adipose tissue, and the pancreatic islets. Using genetically engineered mice, we examine the whole body physiology as well as take biological, biochemical and molecular approaches to define physiological roles in specific tissues, in addition to defining its potential pathogenic role in diabetes. These approaches to clarify tissue-specific molecular mechanisms have wide implications for treatment of both type 1 and type 2 diabetes.

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